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The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells

BACKGROUND: Resistance to taxane-based therapy in breast cancer patients is a major clinical problem that may be addressed through insight of the genomic alterations leading to taxane resistance in breast cancer cells. In the current study we used whole exome sequencing to discover somatic genomic a...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:BMC Genomics
Päätekijät: Hansen, Stine Ninel, Ehlers, Natasja Spring, Zhu, Shida, Thomsen, Mathilde Borg Houlberg, Nielsen, Rikke Linnemann, Liu, Dongbing, Wang, Guangbiao, Hou, Yong, Zhang, Xiuqing, Xu, Xun, Bolund, Lars, Yang, Huanming, Wang, Jun, Moreira, Jose, Ditzel, Henrik J, Brünner, Nils, Schrohl, Anne-Sofie, Stenvang, Jan, Gupta, Ramneek
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899892/
https://ncbi.nlm.nih.gov/pubmed/27277198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2749-4
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