Lataa...
Evolutionary dynamics of tumor suppressor gene inactivation
Tumor suppressor genes (TSGs) are important gatekeepers that protect against somatic evolution of cancer. Losing both alleles of a TSG in a single cell represents a step toward cancer. We study how the kinetics of TSG inactivation depends on the population size of cells and the mutation rates for th...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2004
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC489986/ https://ncbi.nlm.nih.gov/pubmed/15252197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400747101 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|