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Foci of cyclin A2 interact with actin and RhoA in mitosis

Cyclin A2 is a key player in the regulation of the cell cycle. Its degradation in mid-mitosis depends primarily on the ubiquitin-proteasome system (UPS), while autophagy also contributes. However, a fraction of cyclin A2 persists beyond metaphase. In this work, we focus on cyclin A2-rich foci detect...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Loukil, Abdelhalim, Izard, Fanny, Georgieva, Mariya, Mashayekhan, Shaereh, Blanchard, Jean-Marie, Parmeggiani, Andrea, Peter, Marion
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899731/
https://ncbi.nlm.nih.gov/pubmed/27279564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27215
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