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A novel function for Cyclin A2: Control of cell invasion via RhoA signaling

Cyclin A2 plays a key role in cell cycle regulation. It is essential in embryonic cells and in the hematopoietic lineage yet dispensable in fibroblasts. In this paper, we demonstrate that Cyclin A2–depleted cells display a cortical distribution of actin filaments and increased migration. These defec...

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Detalhes bibliográficos
Main Authors: Arsic, Nikola, Bendris, Nawal, Peter, Marion, Begon-Pescia, Christina, Rebouissou, Cosette, Gadéa, Gilles, Bouquier, Nathalie, Bibeau, Frédéric, Lemmers, Bénédicte, Blanchard, Jean Marie
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255987/
https://ncbi.nlm.nih.gov/pubmed/22232705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201102085
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