Drug-induced reactive oxygen species (ROS) rely on cell membrane properties to exert anticancer effects

Pharmacological concentrations of small molecule natural products, such as ascorbic acid, have exhibited distinct cell killing outcomes between cancer and normal cells whereby cancer cells undergo apoptosis or necrosis while normal cells are not adversely affected. Here, we develop a mathematical mo...

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Vydáno v:Sci Rep
Hlavní autoři: Molavian, Hamid R., Goldman, Aaron, Phipps, Colin J., Kohandel, Mohammad, Wouters, Bradly G., Sengupta, Shiladitya, Sivaloganathan, Sivabal
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899687/
https://ncbi.nlm.nih.gov/pubmed/27278439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27439
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