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Drug-induced reactive oxygen species (ROS) rely on cell membrane properties to exert anticancer effects

Pharmacological concentrations of small molecule natural products, such as ascorbic acid, have exhibited distinct cell killing outcomes between cancer and normal cells whereby cancer cells undergo apoptosis or necrosis while normal cells are not adversely affected. Here, we develop a mathematical mo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Molavian, Hamid R., Goldman, Aaron, Phipps, Colin J., Kohandel, Mohammad, Wouters, Bradly G., Sengupta, Shiladitya, Sivaloganathan, Sivabal
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899687/
https://ncbi.nlm.nih.gov/pubmed/27278439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27439
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