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Blockage of Autophagy Rescues the Dual PI3K/mTOR Inhibitor BEZ235-induced Growth Inhibition of Colorectal Cancer Cells

Molecular targeting for the altered signaling pathways has been proven to be effective for the treatment ofmany types of human cancer, including colorectal cancer (CRC). The dual phosphatidylinositol-3-kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitor BEZ235 has shown to exhibit poten...

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Detalhes bibliográficos
Publicado no:Dev Reprod
Main Authors: Oh, Iljoong, Cho, Hyunchul, Lee, Yonghoon, Cheon, Minseok, Park, Deokbae, Lee, Youngki
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Developmental Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899554/
https://ncbi.nlm.nih.gov/pubmed/27294206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12717/DR.2016.20.1.001
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