Expansion of epigenetic alterations in EFEMP1 promoter predicts malignant formation in pancreatobiliary intraductal papillary mucinous neoplasms

PURPOSE: Although limited understanding exists for the presence of specific genetic mutations and aberrantly methylated genes in pancreatobiliary intraductal papillary mucinous neoplasms (IPMNs), the fundamental understanding of the dynamics of methylation expansion across CpG dinucleotides in speci...

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Publicado en:J Cancer Res Clin Oncol
Autores principales: Yoshida, Kazuhiro, Nagasaka, Takeshi, Umeda, Yuzo, Tanaka, Takehiro, Kimura, Keisuke, Taniguchi, Fumitaka, Fuji, Tomokazu, Shigeyasu, Kunitoshi, Mori, Yoshiko, Yanai, Hiroyuki, Yagi, Takahito, Goel, Ajay, Fujiwara, Toshiyoshi
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article – Clinical Oncology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899496/
https://ncbi.nlm.nih.gov/pubmed/27095449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-016-2164-x
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