Clinical Significance of MLH1 Methylation and CpG Island Methylator Phenotype as Prognostic Markers in Patients with Gastric Cancer

BACKGROUND: To improve the outcome of patients suffering from gastric cancer, a better understanding of underlying genetic and epigenetic events in this malignancy is required. Although CpG island methylator phenotype (CIMP) and microsatellite instability (MSI) have been shown to play pivotal roles...

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Udgivet i:PLoS One
Main Authors: Shigeyasu, Kunitoshi, Nagasaka, Takeshi, Mori, Yoshiko, Yokomichi, Naosuke, Kawai, Takashi, Fuji, Tomokazu, Kimura, Keisuke, Umeda, Yuzo, Kagawa, Shunsuke, Goel, Ajay, Fujiwara, Toshiyoshi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488282/
https://ncbi.nlm.nih.gov/pubmed/26121593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130409
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