Heterogeneity of Epigenetic and Epithelial Mesenchymal Transition Marks in Hepatocellular Carcinoma with Keratin 19 Proficiency

OBJECTIVE: Keratin 19 (K19) expression is a potential predictor of poor prognosis in patients with hepatocellular carcinoma (HCC). To clarify the feature of K19-proficient HCC, we traced epigenetic footprints in cultured cells and clinical materials. PATIENTS AND METHODS: In vitro, KRT19 promoter me...

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Detalhes bibliográficos
Publicado no:Liver Cancer
Main Authors: Yokomichi, Naosuke, Nishida, Naoshi, Umeda, Yuzo, Taniguchi, Fumitaka, Yasui, Kazuya, Toshima, Toshiaki, Mori, Yoshiko, Nyuya, Akihiro, Tanaka, Takehiro, Yamada, Takeshi, Yagi, Takahito, Fujiwara, Toshiyoshi, Yamaguchi, Yoshiyuki, Goel, Ajay, Kudo, Masatoshi, Nagasaka, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2019
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738240/
https://ncbi.nlm.nih.gov/pubmed/31602368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000490806
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