PIAS1 Promotes Lymphomagenesis Through MYC Upregulation

The MYC proto-oncogene is a transcription factor implicated in a broad range of cancers. MYC is regulated by several post-translational modifications including SUMOylation, but the functional impact of this post-translational modification is still unclear. Here we report that the SUMO E3 ligase PIAS...

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Udgivet i:Cell Rep
Main Authors: Rabellino, Andrea, Melegari, Margherita, Tompkins, Van S., Chen, Weina, Van Ness, Brian G., Teruya-Feldstein, Julie, Conacci-Sorrell, Maralice, Janz, Siegfried, Scaglioni, Pier Paolo
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899214/
https://ncbi.nlm.nih.gov/pubmed/27239040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.015
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