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FUNCTIONALLY CONSERVATIVE SUBSTITUTIONS AT CARDIAC TROPONIN I S43/45

A phospho-null Ala substitution at protein kinase C (PKC)-targeted cardiac troponin I (cTnI) S43/45 reduces myocyte and cardiac contractile function. The goal of the current study was to test whether cTnIS43/45N is an alternative, functionally conservative substitution in cardiac myocytes. Partial a...

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Détails bibliographiques
Publié dans:Arch Biochem Biophys
Auteurs principaux: Lang, Sarah E., Stevenson, Tamara K., Xu, Dongyang, O’Connell, Ryan, Westfall, Margaret V.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899172/
https://ncbi.nlm.nih.gov/pubmed/26869200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2016.02.002
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