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Unravelling the structural plasticity of stretched DNA under torsional constraint

Regions of the genome are often held under torsional constraint. Nevertheless, the influence of such constraint on DNA–protein interactions during genome metabolism is still poorly understood. Here using a combined optical tweezers and fluorescence microscope, we quantify and explain how torsional c...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: King, Graeme A., Peterman, Erwin J. G., Wuite, Gijs J. L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4897764/
https://ncbi.nlm.nih.gov/pubmed/27263853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11810
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