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Unravelling the structural plasticity of stretched DNA under torsional constraint

Regions of the genome are often held under torsional constraint. Nevertheless, the influence of such constraint on DNA–protein interactions during genome metabolism is still poorly understood. Here using a combined optical tweezers and fluorescence microscope, we quantify and explain how torsional c...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: King, Graeme A., Peterman, Erwin J. G., Wuite, Gijs J. L.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4897764/
https://ncbi.nlm.nih.gov/pubmed/27263853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11810
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