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Cardiac arrest triggers hippocampal neuronal death through autophagic and apoptotic pathways

The mechanism of neuronal death induced by ischemic injury remains unknown. We investigated whether autophagy and p53 signaling played a role in the apoptosis of hippocampal neurons following global cerebral ischemia-reperfusion (I/R) injury, in a rat model of 8-min asphyxial cardiac arrest (CA) and...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cui, Derong, Shang, Hanbing, Zhang, Xiaoli, Jiang, Wei, Jia, Xiaofeng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4897701/
https://ncbi.nlm.nih.gov/pubmed/27273382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27642
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