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Mitochondrial and apoptotic neuronal death signaling pathways in cerebral ischemia

Mitochondria play important roles as the powerhouse of the cell. After cerebral ischemia, mitochondria overproduce reactive oxygen species (ROS), which have been thoroughly studied with the use of superoxide dismutase transgenic or knockout animals. ROS directly damage lipids, proteins, and nucleic...

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Autores principales: Niizuma, Kuniyasu, Yoshioka, Hideyuki, Chen, Hai, Kim, Gab Seok, Jung, Joo Eun, Katsu, Masataka, Okami, Nobuya, Chan, Pak H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790539/
https://ncbi.nlm.nih.gov/pubmed/19751828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2009.09.002
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