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Computational support for a scaffolding mechanism of centriole assembly

Centrioles are essential for forming cilia, flagella and centrosomes. Successful centriole assembly requires proteins of the SAS-6 family, which can form oligomeric ring structures with ninefold symmetry in vitro. While important progress has been made in understanding SAS-6 protein biophysics, the...

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Publicado en:Sci Rep
Autores principales: Klein, Heinrich C. R., Guichard, Paul, Hamel, Virginie, Gönczy, Pierre, Schwarz, Ulrich S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4897622/
https://ncbi.nlm.nih.gov/pubmed/27272020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27075
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