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Electrophysiologist shows a cation channel function of MLKL

Whether mixed lineage kinase domain-like (MLKL) mediates necroptosis by forming ion channel, none-selective pore, or simply by disrupting plasma membrane is unclear. In a paper published in recent issue of Cell Research, Xia et al. showed that MLKL functions as a novel class of cation channel.

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Zhang, Yingying, Han, Jiahuai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4897189/
https://ncbi.nlm.nih.gov/pubmed/27229313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.64
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