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Modulation of Autophagy by Sorafenib: Effects on Treatment Response

The multikinase inhibitor sorafenib is, at present, the only drug approved for the treatment of hepatocellular carcinoma (HCC), one of the most lethal types of cancer worldwide. However, the increase in the number of sorafenib tumor resistant cells reduces efficiency. A better knowledge of the intra...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Prieto-Domínguez, Nestor, Ordóñez, Raquel, Fernández, Anna, García-Palomo, Andres, Muntané, Jordi, González-Gallego, Javier, Mauriz, José L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896953/
https://ncbi.nlm.nih.gov/pubmed/27375485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00151
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