A carregar...
Suicide gene approach using a dual-expression lentiviral vector to enhance the safety of ex vivo gene therapy for bone repair
‘Ex vivo’ gene therapy using viral vectors to overexpress BMP-2 is shown to heal critical-sized bone defects in experimental animals. To increase its safety, we constructed a dual-expression lentiviral vector to overexpress BMP-2 or luciferase and an HSV1-tk analog, Δtk (LV-Δtk-T2A-BMP-2/Luc). We hy...
Na minha lista:
| Publicado no: | Gene Ther |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4896754/ https://ncbi.nlm.nih.gov/pubmed/24285218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2013.66 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|