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Safety and efficacy of DNA vaccines: Plasmids vs. minicircles

While DNA vaccination using plasmid vectors is highly attractive, there is a need for further vector optimization regarding safety, stability, and efficiency. In this commentary, we review the minicircle vector (MC), which is an entity devoid of plasmid bacterial sequences, as an alternative to the...

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書目詳細資料
發表在:Hum Vaccin Immunother
Main Authors: Stenler, Sofia, Blomberg, Pontus, Smith, CI Edvard
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2014
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896608/
https://ncbi.nlm.nih.gov/pubmed/24553064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.28077
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