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Safety and efficacy of DNA vaccines: Plasmids vs. minicircles

While DNA vaccination using plasmid vectors is highly attractive, there is a need for further vector optimization regarding safety, stability, and efficiency. In this commentary, we review the minicircle vector (MC), which is an entity devoid of plasmid bacterial sequences, as an alternative to the...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Hum Vaccin Immunother
Главные авторы: Stenler, Sofia, Blomberg, Pontus, Smith, CI Edvard
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896608/
https://ncbi.nlm.nih.gov/pubmed/24553064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.28077
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