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Safety and efficacy of DNA vaccines: Plasmids vs. minicircles

While DNA vaccination using plasmid vectors is highly attractive, there is a need for further vector optimization regarding safety, stability, and efficiency. In this commentary, we review the minicircle vector (MC), which is an entity devoid of plasmid bacterial sequences, as an alternative to the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hum Vaccin Immunother
Hauptverfasser: Stenler, Sofia, Blomberg, Pontus, Smith, CI Edvard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896608/
https://ncbi.nlm.nih.gov/pubmed/24553064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.28077
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