Immunotherapy of tuberculosis with Mycobacterium leprae Hsp65 as a DNA vaccine triggers cross-reactive antibodies against mammalian Hsp60 but not pathological autoimmunity

Despite substantial efforts in recent years toward the development of new vaccines and drugs against tuberculosis (TB), success has remained elusive. Immunotherapy of TB with mycobacterial Hsp65 as a DNA vaccine (DNA-hsp65) results in a reduction of systemic bacterial loads and lung tissue damage, b...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Wydane w:Hum Vaccin Immunother
Główni autorzy: Doimo, Nayara TS, Zárate-Bladés, Carlos R, Rodrigues, Rodrigo F, Tefé-Silva, Cristiane, Trotte, Marcele NS, Souza, Patrícia RM, Soares, Luana S, Rios, Wendy M, Floriano, Elaine M, Brandão, Izaira T, Masson, Ana P, Coelho, Verônica, Ramos, Simone G, Silva, Celio L
Format: Artigo
Język:Inglês
Wydane: Taylor & Francis 2014
Hasła przedmiotowe:
Short Report
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896578/
https://ncbi.nlm.nih.gov/pubmed/24607935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.28249
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