Combined immunization using DNA-Sm14 and DNA-Hsp65 increases CD8+ memory T cells, reduces chronic pathology and decreases egg viability during Schistosoma mansoni infection

BACKGROUND: Schistosomiasis is one of the most important neglected diseases found in developing countries and affects 249 million people worldwide. The development of an efficient vaccination strategy is essential for the control of this disease. Previous work showed partial protection induced by DN...

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מידע ביבליוגרפי
Main Authors: Espíndola, Milena Sobral, Frantz, Fabiani Gai, Soares, Luana Silva, Masson, Ana Paula, Tefé-Silva, Cristiane, Bitencourt, Claudia Silva, Oliveira, Sérgio Costa, Rodrigues, Vanderlei, Ramos, Simone Gusmão, Silva, Célio Lopes, Faccioli, Lúcia Helena
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2014
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031977/
https://ncbi.nlm.nih.gov/pubmed/24886395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-14-263
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