Bone morphogenetic protein signaling promotes tumorigenesis in a murine model of high-grade glioma

BACKGROUND: Improved therapies for high-grade glioma (HGG) are urgently needed as the median survival for grade IV gliomas is only 15 months. Bone morphogenetic protein (BMP) signaling plays critical and complex roles in many types of cancer, including glioma, with most of the recently published wor...

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Vydáno v:Neuro Oncol
Hlavní autoři: Hover, Laura D., Owens, Philip, Munden, Alexander L., Wang, Jialiang, Chambless, Lola B., Hopkins, Corey R., Hong, Charles C., Moses, Harold L., Abel, Ty W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896540/
https://ncbi.nlm.nih.gov/pubmed/26683138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov310
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