Bone morphogenetic protein signaling promotes tumorigenesis in a murine model of high-grade glioma

BACKGROUND: Improved therapies for high-grade glioma (HGG) are urgently needed as the median survival for grade IV gliomas is only 15 months. Bone morphogenetic protein (BMP) signaling plays critical and complex roles in many types of cancer, including glioma, with most of the recently published wor...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Hover, Laura D., Owens, Philip, Munden, Alexander L., Wang, Jialiang, Chambless, Lola B., Hopkins, Corey R., Hong, Charles C., Moses, Harold L., Abel, Ty W.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Basic and Translational Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896540/
https://ncbi.nlm.nih.gov/pubmed/26683138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov310
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