Bone morphogenetic protein signaling promotes tumorigenesis in a murine model of high-grade glioma

BACKGROUND: Improved therapies for high-grade glioma (HGG) are urgently needed as the median survival for grade IV gliomas is only 15 months. Bone morphogenetic protein (BMP) signaling plays critical and complex roles in many types of cancer, including glioma, with most of the recently published wor...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Hover, Laura D., Owens, Philip, Munden, Alexander L., Wang, Jialiang, Chambless, Lola B., Hopkins, Corey R., Hong, Charles C., Moses, Harold L., Abel, Ty W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896540/
https://ncbi.nlm.nih.gov/pubmed/26683138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov310
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