Bone morphogenetic protein signaling promotes tumorigenesis in a murine model of high-grade glioma

BACKGROUND: Improved therapies for high-grade glioma (HGG) are urgently needed as the median survival for grade IV gliomas is only 15 months. Bone morphogenetic protein (BMP) signaling plays critical and complex roles in many types of cancer, including glioma, with most of the recently published wor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Hover, Laura D., Owens, Philip, Munden, Alexander L., Wang, Jialiang, Chambless, Lola B., Hopkins, Corey R., Hong, Charles C., Moses, Harold L., Abel, Ty W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Basic and Translational Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896540/
https://ncbi.nlm.nih.gov/pubmed/26683138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov310
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