Inhibition of Soluble Epoxide Hydrolase Limits Mitochondrial Damage and Preserves Function Following Ischemic Injury

Aims: Myocardial ischemia can result in marked mitochondrial damage leading to cardiac dysfunction, as such identifying novel mechanisms to limit mitochondrial injury is important. This study investigated the hypothesis that inhibiting soluble epoxide hydrolase (sEH), responsible for converting epox...

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Bibliografische gegevens
Gepubliceerd in:Front Pharmacol
Hoofdauteurs: Akhnokh, Maria K., Yang, Feng Hua, Samokhvalov, Victor, Jamieson, Kristi L., Cho, Woo Jung, Wagg, Cory, Takawale, Abhijit, Wang, Xiuhua, Lopaschuk, Gary D., Hammock, Bruce D., Kassiri, Zamaneh, Seubert, John M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2016
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896112/
https://ncbi.nlm.nih.gov/pubmed/27375480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00133
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