Deficiency of Soluble Epoxide Hydrolase Protects Cardiac Function Impaired by LPS-Induced Acute Inflammation

Lipopolysaccharide (LPS) is a bacterial wall endotoxin producing many pathophysiological conditions including myocardial inflammation leading to cardiotoxicity. Linoleic acid (18:2n6, LA) is an essential n-6 PUFA which is converted to arachidonic acid (20:4n6, AA) by desaturation and elongation via...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Samokhvalov, Victor, Jamieson, K. Lockhart, Darwesh, Ahmed M., Keshavarz-Bahaghighat, Hedieh, Lee, Tim Y. T., Edin, Matthew, Lih, Fred, Zeldin, Darryl C., Seubert, John M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6339940/
https://ncbi.nlm.nih.gov/pubmed/30692927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01572
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