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In vitro and in vivo correlates of physiological and neoplastic human Fallopian tube stem cells

High-grade serous cancer (HGSC) progresses to advanced stages without symptoms and the 5-year survival rate is a dismal 30%. Recent studies of ovaries and Fallopian tubes in patients with BRCA1 or BRCA2 mutations have documented a pre-metastatic intramucosal neoplasm that is found almost exclusively...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Pathol
Hauptverfasser: Yamamoto, Yusuke, Ning, Gang, Howitt, Brooke E, Mehra, Karishma, Wu, Lingyan, Wang, Xia, Hong, Yue, Kern, Florian, Wei, Tay Seok, Zhang, Ting, Nagarajan, Niranjan, Basuli, Debargha, Torti, Suzy, Brewer, Molly, Choolani, Mahesh, McKeon, Frank, Crum, Christopher P, Xian, Wa
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895925/
https://ncbi.nlm.nih.gov/pubmed/26415052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4649
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