The PAX2-null immunophenotype defines multiple lineages with common expression signatures in benign and neoplastic oviductal epithelium

The oviducts contain high grade serous cancer (HGSC) precursors (serous tubal intraepithelial neoplasia or STINs), which are γ-H2AX(p)- and TP53 mutation-positive. Although they express wild type p53, secretory cell outgrowths (SCOUTs) are associated with older age and serous cancer; moreover both S...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Pathol
Egile Nagusiak: Ning, Gang, Bijron, Jonathan G., Yamamoto, Yusuke, Wang, Xia, Howitt, Brooke E., Herfs, Michael, Yang, Eric, Hong, Yue, Cornille, Maxence, Wu, Lingyan, Hanamornroongruang, Suchanan, McKeon, Frank D., Crum, Christopher P., Xian, Wa
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229427/
https://ncbi.nlm.nih.gov/pubmed/25130537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4417
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