The PAX2-null immunophenotype defines multiple lineages with common expression signatures in benign and neoplastic oviductal epithelium

The oviducts contain high grade serous cancer (HGSC) precursors (serous tubal intraepithelial neoplasia or STINs), which are γ-H2AX(p)- and TP53 mutation-positive. Although they express wild type p53, secretory cell outgrowths (SCOUTs) are associated with older age and serous cancer; moreover both S...

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Détails bibliographiques
Publié dans:J Pathol
Auteurs principaux: Ning, Gang, Bijron, Jonathan G., Yamamoto, Yusuke, Wang, Xia, Howitt, Brooke E., Herfs, Michael, Yang, Eric, Hong, Yue, Cornille, Maxence, Wu, Lingyan, Hanamornroongruang, Suchanan, McKeon, Frank D., Crum, Christopher P., Xian, Wa
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229427/
https://ncbi.nlm.nih.gov/pubmed/25130537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4417
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