Tenascin-C drives persistence of organ fibrosis

The factors responsible for maintaining persistent organ fibrosis in systemic sclerosis (SSc) are not known but emerging evidence implicates toll-like receptors (TLRs) in the pathogenesis of SSc. Here we show the expression, mechanism of action and pathogenic role of endogenous TLR activators in ski...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Bhattacharyya, Swati, Wang, Wenxia, Morales-Nebreda, Luisa, Feng, Gang, Wu, Minghua, Zhou, Xiaodong, Lafyatis, Robert, Lee, Jungwha, Hinchcliff, Monique, Feghali-Bostwick, Carol, Lakota, Katja, Budinger, G. R. Scott, Raparia, Kirtee, Tamaki, Zenshiro, Varga, John
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895803/
https://ncbi.nlm.nih.gov/pubmed/27256716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11703
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