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Inference of domain-disease associations from domain-protein, protein-disease and disease-disease relationships

BACKGROUND: Protein domains can be viewed as portable units of biological function that defines the functional properties of proteins. Therefore, if a protein is associated with a disease, protein domains might also be associated and define disease endophenotypes. However, knowledge about such domai...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Zhang, Wangshu, Coba, Marcelo P., Sun, Fengzhu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895779/
https://ncbi.nlm.nih.gov/pubmed/26818594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-015-0247-y
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