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Integrating multiple protein-protein interaction networks to prioritize disease genes: a Bayesian regression approach

BACKGROUND: The identification of genes responsible for human inherited diseases is one of the most challenging tasks in human genetics. Recent studies based on phenotype similarity and gene proximity have demonstrated great success in prioritizing candidate genes for human diseases. However, most o...

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Detalhes bibliográficos
Main Authors: Zhang, Wangshu, Sun, Fengzhu, Jiang, Rui
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044265/
https://ncbi.nlm.nih.gov/pubmed/21342540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S1-S11
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