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Integrating multiple protein-protein interaction networks to prioritize disease genes: a Bayesian regression approach

BACKGROUND: The identification of genes responsible for human inherited diseases is one of the most challenging tasks in human genetics. Recent studies based on phenotype similarity and gene proximity have demonstrated great success in prioritizing candidate genes for human diseases. However, most o...

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Hlavní autoři: Zhang, Wangshu, Sun, Fengzhu, Jiang, Rui
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044265/
https://ncbi.nlm.nih.gov/pubmed/21342540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S1-S11
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