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Integrating multiple protein-protein interaction networks to prioritize disease genes: a Bayesian regression approach

BACKGROUND: The identification of genes responsible for human inherited diseases is one of the most challenging tasks in human genetics. Recent studies based on phenotype similarity and gene proximity have demonstrated great success in prioritizing candidate genes for human diseases. However, most o...

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Autors principals: Zhang, Wangshu, Sun, Fengzhu, Jiang, Rui
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044265/
https://ncbi.nlm.nih.gov/pubmed/21342540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S1-S11
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