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Inferring domain-domain interactions from protein-protein interactions in the complex network conformation

BACKGROUND: As protein domains are functional and structural units of proteins, a large proportion of protein-protein interactions (PPIs) are achieved by domain-domain interactions (DDIs), many computational efforts have been made to identify DDIs from experimental PPIs since high throughput technol...

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Autori principali: Chen, Chen, Zhao, Jun-Fei, Huang, Qiang, Wang, Rui-Sheng, Zhang, Xiang-Sun
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403472/
https://ncbi.nlm.nih.gov/pubmed/23046795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-S1-S7
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