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Cohesin and Human Disease

Cornelia de Lange syndrome (CdLS) is a dominant multisystem disorder caused by a disruption of cohesin function. The cohesin ring complex is composed of four protein subunits and more than 25 additional proteins involved in its regulation. The discovery that this complex also has a fundamental role...

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Detalhes bibliográficos
Publicado no:Annu Rev Genomics Hum Genet
Main Authors: Liu, Jinglan, Krantz, Ian D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894839/
https://ncbi.nlm.nih.gov/pubmed/18767966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.genom.9.081307.164211
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