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Cohesin and Human Disease

Cornelia de Lange syndrome (CdLS) is a dominant multisystem disorder caused by a disruption of cohesin function. The cohesin ring complex is composed of four protein subunits and more than 25 additional proteins involved in its regulation. The discovery that this complex also has a fundamental role...

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Enregistré dans:
Détails bibliographiques
Publié dans:Annu Rev Genomics Hum Genet
Auteurs principaux: Liu, Jinglan, Krantz, Ian D.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894839/
https://ncbi.nlm.nih.gov/pubmed/18767966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.genom.9.081307.164211
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