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Inhibition of poly(adenosine diphosphate-ribose) polymerase attenuates ventilator-induced lung injury
BACKGROUND: Mechanical ventilation can induce organ injury associated with overwhelming inflammatory responses. Excessive activation of poly(adenosine diphosphate-ribose) polymerase enzyme following massive DNA damage may aggravate inflammatory responses. We thus hypothesized that the pharmacologica...
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| Publicado en: | Anesthesiology |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4894820/ https://ncbi.nlm.nih.gov/pubmed/18212571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.anes.0000299434.86640.15 |
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