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Synchronization of endothelial Dll4-Notch dynamics switch blood vessels from branching to expansion

Formation of a regularly branched blood vessel network is crucial in development and physiology. Here we show that the expression of the Notch ligand Dll4 fluctuates in individual endothelial cells within sprouting vessels in the mouse retina in vivo and in correlation with dynamic cell movement in...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Ubezio, Benedetta, Blanco, Raquel Agudo, Geudens, Ilse, Stanchi, Fabio, Mathivet, Thomas, Jones, Martin L, Ragab, Anan, Bentley, Katie, Gerhardt, Holger
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894757/
https://ncbi.nlm.nih.gov/pubmed/27074663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12167
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