Dynamic Endothelial Cell Rearrangements Drive Developmental Vessel Regression

Patterning of functional blood vessel networks is achieved by pruning of superfluous connections. The cellular and molecular principles of vessel regression are poorly understood. Here we show that regression is mediated by dynamic and polarized migration of endothelial cells, representing anastomos...

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Detalles Bibliográficos
Publicado en:PLoS Biol
Main Authors: Franco, Claudio A., Jones, Martin L., Bernabeu, Miguel O., Geudens, Ilse, Mathivet, Thomas, Rosa, Andre, Lopes, Felicia M., Lima, Aida P., Ragab, Anan, Collins, Russell T., Phng, Li-Kun, Coveney, Peter V., Gerhardt, Holger
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401640/
https://ncbi.nlm.nih.gov/pubmed/25884288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002125
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