Dynamic Endothelial Cell Rearrangements Drive Developmental Vessel Regression

Patterning of functional blood vessel networks is achieved by pruning of superfluous connections. The cellular and molecular principles of vessel regression are poorly understood. Here we show that regression is mediated by dynamic and polarized migration of endothelial cells, representing anastomos...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Franco, Claudio A., Jones, Martin L., Bernabeu, Miguel O., Geudens, Ilse, Mathivet, Thomas, Rosa, Andre, Lopes, Felicia M., Lima, Aida P., Ragab, Anan, Collins, Russell T., Phng, Li-Kun, Coveney, Peter V., Gerhardt, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401640/
https://ncbi.nlm.nih.gov/pubmed/25884288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002125
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