Macroscopic and Macromolecular Specificity of Alkylphenol Anesthetics for Neuronal Substrates

We used a photoactive general anesthetic called meta-azi-propofol (AziPm) to test the selectivity and specificity of alkylphenol anesthetic binding in mammalian brain. Photolabeling of rat brain sections with [(3)H]AziPm revealed widespread but heterogeneous ligand distribution, with [(3)H]AziPm pre...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Weiser, Brian P., Hall, Michael A., Weinbren, Nathan L., Woll, Kellie A., Dailey, William P., Eckenhoff, Maryellen F., Eckenhoff, Roderic G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894431/
https://ncbi.nlm.nih.gov/pubmed/25853337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09695
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