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Shutting Down the Pore: The Search for Small Molecule Inhibitors of the Mitochondrial Permeability Transition
The mitochondrial permeability transition pore (PTP) is now recognized as playing a key role in a wide variety of human diseases whose common pathology may be based in mitochondrial dysfunction. Recently, PTP assays have been adapted to high-throughput screening approaches to identify small molecule...
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| Publicado en: | Biochim Biophys Acta |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4893955/ https://ncbi.nlm.nih.gov/pubmed/26924772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2016.02.016 |
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