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A potential structural switch for regulating DNA-binding by TEAD transcription factors

TEA domain transcription factors (TEAD) are essential for normal development of eukaryotes and are the downstream effectors of the Hippo tumor suppressor pathway. Whereas our earlier work established the three-dimensional structure of the highly conserved DNA binding domain using solution NMR spectr...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Lee, Dong-Sun, Vonrhein, Clemens, Albarado, Diana, Raman, C. S., Veeraraghavan, Sudha
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893915/
https://ncbi.nlm.nih.gov/pubmed/27016204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.03.008
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