A Validated UHPLC-Tandem Mass Spectrometry Method for Quantitative Analysis of Flavonolignans in Milk Thistle (Silybum marianum) Extracts

Validated methods are needed for the analysis of natural product secondary metabolites. These methods are particularly important to translate in vitro observations to in vivo studies. Herein, a method is reported for the analysis of the key secondary metabolites, a series of flavonolignans and a fla...

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Publicat a:J Pharm Biomed Anal
Autors principals: Graf, Tyler N., Cech, Nadja B., Polyak, Stephen J., Oberlies, Nicholas H.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893890/
https://ncbi.nlm.nih.gov/pubmed/27136284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2016.04.028
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