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Adaptive and Acquired Resistance to EGFR Inhibitors Converge on the MAPK Pathway
Both adaptive and acquired resistance significantly limits the efficacy of the epidermal growth factor receptor (EGFR) kinase inhibitors. However, the distinct or common mechanisms of adaptive and acquired resistance have not been fully characterized. Here, through systematic modeling of erlotinib r...
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出版年: | Theranostics |
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主要な著者: | , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
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Ivyspring International Publisher
2016
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4893648/ https://ncbi.nlm.nih.gov/pubmed/27279914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.14409 |
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