Adaptive and Acquired Resistance to EGFR Inhibitors Converge on the MAPK Pathway

Both adaptive and acquired resistance significantly limits the efficacy of the epidermal growth factor receptor (EGFR) kinase inhibitors. However, the distinct or common mechanisms of adaptive and acquired resistance have not been fully characterized. Here, through systematic modeling of erlotinib r...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Theranostics
Egile Nagusiak: Ma, Pengfei, Fu, Yujie, Chen, Minjiang, Jing, Ying, Wu, Jie, Li, Ke, Shen, Ying, Gao, Jian-Xin, Wang, Mengzhao, Zhao, Xiaojing, Zhuang, Guanglei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Ivyspring International Publisher 2016
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893648/
https://ncbi.nlm.nih.gov/pubmed/27279914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.14409
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