Adaptive and Acquired Resistance to EGFR Inhibitors Converge on the MAPK Pathway

Both adaptive and acquired resistance significantly limits the efficacy of the epidermal growth factor receptor (EGFR) kinase inhibitors. However, the distinct or common mechanisms of adaptive and acquired resistance have not been fully characterized. Here, through systematic modeling of erlotinib r...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Theranostics
Κύριοι συγγραφείς: Ma, Pengfei, Fu, Yujie, Chen, Minjiang, Jing, Ying, Wu, Jie, Li, Ke, Shen, Ying, Gao, Jian-Xin, Wang, Mengzhao, Zhao, Xiaojing, Zhuang, Guanglei
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Ivyspring International Publisher 2016
Θέματα:
Research Paper
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893648/
https://ncbi.nlm.nih.gov/pubmed/27279914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.14409
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια