MiR675-5p Acts on HIF-1α to Sustain Hypoxic Responses: A New Therapeutic Strategy for Glioma

Hypoxia is a common feature in solid tumours. In glioma, it is considered the major driving force for tumour angiogenesis and correlates with enhanced resistance to conventional therapies, increased invasiveness and a poor prognosis for patients. Here we describe, for the first time, that miR675-5p,...

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Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Lo Dico, Alessia, Costa, Viviana, Martelli, Cristina, Diceglie, Cecilia, Rajata, Francesca, Rizzo, Aroldo, Mancone, Carmine, Tripodi, Marco, Ottobrini, Luisa, Alessandro, Riccardo, Conigliaro, Alice
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893639/
https://ncbi.nlm.nih.gov/pubmed/27279905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.14700
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