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Sustained E2F-Dependent Transcription Is a Key Mechanism to Prevent Replication-Stress-Induced DNA Damage

Recent work established DNA replication stress as a crucial driver of genomic instability and a key event at the onset of cancer. Post-translational modifications play an important role in the cellular response to replication stress by regulating the activity of key components to prevent replication...

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Dades bibliogràfiques
Publicat a:Cell Rep
Autors principals: Bertoli, Cosetta, Herlihy, Anna E., Pennycook, Betheney R., Kriston-Vizi, Janos, de Bruin, Robertus A.M.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893157/
https://ncbi.nlm.nih.gov/pubmed/27160911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.036
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